Predictors of Primary Graft Dysfunction Following Bilateral Lung Transplantation
نویسندگان
چکیده
منابع مشابه
Primary Graft Dysfunction After Lung Transplantation.
Primary graft dysfunction is a form of acute injury after lung transplantation that is associated with significant short- and long-term morbidity and mortality. Multiple mechanisms contribute to the pathogenesis of primary graft dysfunction, including ischemia reperfusion injury, epithelial cell death, endothelial cell dysfunction, innate immune activation, oxidative stress, and release of infl...
متن کاملLong Term Impact of Primary Graft Dysfunction after Lung Transplantation
According to the International Society for Heart and Lung Transplantation (ISHLT) Registry, graft failure accounted for 24.7% of deaths within 30 days of transplantation among adult lung recipients between 1992 and 2012 [1]. Although important details distinguishing different causes of early graft failure may be missing from the Registry data, it is likely that primary graft dysfunction (PGD) i...
متن کاملGraft calcifications and dysfunction following liver transplantation
BACKGROUND The molecular events, following ischemia and reperfusion (I/R) of the liver during transplantation are largely unknown. There is evidence that apoptotic and necrotic events may take place, and occasionally result in primary graft dysfunction. We herein report two cases, where significant I/R injury correlated with the development of liver calcification and primary liver dysfunction. ...
متن کاملAssociation Between Prolonged Graft Ischemia and Primary Graft Failure or Survival Following Lung Transplantation.
IMPORTANCE The effect of prolonged graft ischemia (≥6 hours) on outcomes following lung transplantation is controversial. OBJECTIVE To evaluate the effect of prolonged total graft ischemia times on long-term survival rates and the development of primary graft failure (PGF) following lung transplantation. DESIGN, SETTING, AND PARTICIPANTS In this retrospective study, the United Network for O...
متن کاملElevated pulmonary artery pressure is a risk factor for primary graft dysfunction following lung transplantation for idiopathic pulmonary fibrosis.
BACKGROUND Idiopathic pulmonary fibrosis (IPF) is often associated with elevations in pulmonary artery pressures. Although primary pulmonary arterial hypertension (PAH) has been associated with primary graft dysfunction (PGD), the role of secondary PAH in mediating PGD risk in patients with IPF is incompletely understood. The purpose of this study was to evaluate the relationship between mean p...
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ژورنال
عنوان ژورنال: The Journal of Heart and Lung Transplantation
سال: 2021
ISSN: 1053-2498
DOI: 10.1016/j.healun.2021.01.1070